After the wonderful support I got via email, I thought I would post this question publicly as others may find the 'hopeful' answer useful.
I'm utilizing the PoolManager middleware (Pathologic Games) to facilitate having many reusable animated sprites. It seems that any animated sprite that is used within this system does not animated correctly.
I've watched the actual tk2dAnimatedSprite script closely, it is indicating that it is playing, it is not paused (or globally paused), the spriteID changes, as does the previous ID ... however the actual rendered sprite does not change.
I have verified that SetFrameInternal is being called as well.
Is there any other suggested points I should be looking at ?
The object pool system simply does a SetActiveRecursive type thing ....
Thoughts?