When anchors are added to the scene then every action that is done in the editor causes you to have to re-save your file. Even saving the file makes it so you have to save the file again.
So, if you are like me and hate to see that asterisk denoting that there is unsaved data in your Unity file or you are trying to work in a team and constantly having an unsaved file is leading to versioning issues, one possible solution is to add:
if(_transform.localPosition != anchoredPosition + new Vector3(offset.x, offset.y, 0))
before line 77 in the 'tk2dCameraAnchor.cs' file. I don't see it causing any issues and it sure does make me less neurotic.